The Path of Tepes did not go very well for about half of the percentage of the UMFE Special Units that went through the process. The chemicals reacted as expected, save that they created antibodies that ate away at the fresh blood cells within the subject's body. This has been recorded as extremely painful, and causes those infected with The Blight to lose control, and forced them to feed on anything near to sate the pain with uninfected blood cells.
Survivors of The Blight, those so unlucky, are apparently able to remember something from their time as a normal human, being able to use weapons, and pilot aircraft, but they have lost the rest of their sanity, and cut and defile themselves, as if to release them from torment in some way. They group together, finding some sort of solitude in space, preying on aircraft passing by, and even landing on planets to raid.